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NIH Highlights Pioneering Research by Drs. Cotten and Marota on using CS-1103 to Reverse Meth Poisoning by Protecting Against Overheating; Low Oxygen Levels; Organ Injury; and Muscle Breakdown
Cambridge, MA | August 2026 A novel drug sequestrant-based therapeutic candidate reverses methamphetamine-induced hyperthermia and hypermetabolism and abates multiorgan toxicity in rats - ScienceDirect In a preclinical study funded by the National Institute on Drug Abuse, CS-1103 protected against methamphetamine overdose, for which there are currently no medications. This pioneering work was conducted by Dr. Joe Cotten, MD, PhD and Dr. Elie Adam, PhD at Mass General Brigham
Sep 1
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